In the future, the colonization spaceship Covenant picks up a strange radio transmission from a previously unknown planet. When some of the Covenant's crew members descend to the planet's surface to investigate, they find a crashed alien spacecraft, along with David (Fassbender), an android from the earlier Prometheus mission, who crashed there many years prior. When some members of the crew begin coming down with an unknown illness, they are put in quarantine, but that won't be enough to stop the alien menace that is unleashed upon the unsuspecting colonists.
When a new family moves into the house next door, 18-year-old Maddy (Stenberg) catches the eye of the family's handsome son, Olly (Robinson), and it doesn't take long before he shows up on Maddy's doorstep offering a neighborly greeting. Maddy's mother, Pauline (Rose), turns Olly away due to Maddy's severe immunodeficiency disease, an illness that's kept her indoors her entire life and allowed her only minimal contact with people outside of her immediate family. The two young lovers, however, won't let the disease get in the way of their romance, no matter the consequences to Maddy's health or life.
Twenty-five years after he married a rich woman more than twice his age, Maximo (Derbez) is thrown out of her opulent mansion when she takes a new, younger lover. Although he was once a womanizer who made a career out of seducing rich older women, in his many years of marriage Maximo let himself get out of shape and out of practice and finds it a struggle to return to his old lifestyle. Luckily, his nephew's (Alejandro) crush has a wealthy grandmother (Welch), upon whom Maximo sets his sights as he tries to get back to his old tricks.