Assuming you mean the late-'80s TV series "In the Heat of the Night," rather than the late-'60s film it was based on, there's actually very little to report.
Though the show was a big hit for NBC, running from 1988 to 1995, none of its stars went on to much afterwards.
There is, of course, a sad element to that, since three of its main stars died shortly after the series ended.
Carroll O'Connor, who played Bill Gillespie, died in 2001 at the age of 76. His adopted son, Hugh, who also starred in the series, committed suicide the year the show left the air. Hugh had struggled with drug addiction most of his life, and it was that addiction that Carroll blamed for the suicide. He had reportedly been sober for the entire run of the series, his only major role, but began using again shortly after its cancelation.
Howard E. Rollins Jr., who played Virgil Tibbs, died in 1996 of complications related to lymphoma.
Of the show's other stars, none have gone on to much success. The busiest has been Anne-Marie Johnson, who played Althea Tibbs for most of the show's run (she left in 1993). She's gone on to a steady career as a supporting star in both film and television. Her most notable roles have included a recurring role as Congresswoman Bobbi Latham in "JAG" in the late '90s and a seven-episode run in the popular teen show "That's So Raven."
The other two main stars, David Hart (who played Parker Williams) and Alan Autry (who played Bubba Skinner), did team up again for a couple of made-for-TV western films, "The Legend of Jake Kincaid" (2002) and a sequel, "Forgiven" (2011). Hart appeared as yet another lawman, Sheriff Bob Logan, while Autry wrote, directed and starred as the titular Jake Kincaid.
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